TLS Online TPP Program

#Question id: 12837


Haploid yeast cells were grown in culture and stained with propidium iodide, a fluorescent dye that is incorporated into DNA. The x axis shows DNA content, the y axis the number of cells. The DNA content analysis shows different populations of cells.

Which of the following statement is correct regarding to above graph?

#Unit 2. Cellular Organization
  1. Cells with unreplicated DNA (1C) and with replicated DNA (2C). The cells between the two peaks represent cells that are in the process of undergoing mitosis.
  2.  Cells with replicated DNA (1C) and with unreplicated DNA (2C). The cells between the two peaks represent cells that are in the process of undergoing DNA replication.
  3. Cells with unreplicated DNA (1C) and with replicated DNA (2C). The cells between the two peaks represent cells that are in the process of undergoing DNA replication.
  4.  Cells with unreplicated DNA (1C) and with replicated DNA (2C). The cells between the two peaks represent cells that are in the process of arrest in G1 phase.
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TLS Online TPP Program

#Question id: 12184

#Unit 2. Cellular Organization

Following graph represent Control of S phase onset in S. cerevisiae by regulated proteolysis of the S phase inhibitor Sic1. 
Which of the following is correct according to graph?

TLS Online TPP Program

#Question id: 12183

#Unit 2. Cellular Organization

Following statements are regarding to regulation of S phase and mitotic cyclin levels in budding yeast.
A. In late anaphase, the anaphase-promoting complex (APC/C) ubiquitinylates S phase and mitotic cyclins.
B. In late anaphase, the anaphase-promoting complex (APC/C) phosphorylates S phase and mitotic cyclins.
C. During exit from mitosis and G1, Cdh1 is dephosphorylated and active; during S phase and mitosis, Cdh1 is phosphorylated and dissociates from APC/C, and APC/C becomes inactive.
D. During exit from mitosis and G1, Cdh1 is phosphorylated and active; during S phase and mitosis, Cdh1 is dephosphorylated and dissociates from APC/C, and APC/C becomes inactive.
E. The G1/S phase CDKs, which themselves are not APC/CCdh1 substrates, phosphorylate Cdh1 at the G1–S phase transition.
F. The G1/S phase CDKs, which themselves are not APC/CCdh1 substrates, ubiquitinylates Cdh1 at the G1–S phase transition.
Which of the following combination is correct?

TLS Online TPP Program

#Question id: 12182

#Unit 2. Cellular Organization

The cell cycle is controlled by protein kinases that comprise a catalytic subunit and a regulatory subunit. Which of the following statement is correct regarding to these subunits?

TLS Online TPP Program

#Question id: 4718

#Unit 2. Cellular Organization

All the following statements about destruction of cyclins are true, except:

TLS Online TPP Program

#Question id: 2994

#Unit 2. Cellular Organization

If a cell has completed meiosis I and the first cytokinesis, and is just beginning meiosis II, which of the following is an appropriate description of its genetic contents?

TLS Online TPP Program

#Question id: 2993

#Unit 2. Cellular Organization

During meiosis, a defect occurs in a cell that results in the failure of spindle microtubules binding at the kinetochores. Which of the following statements describes the most likely result of such a defect?