#Question id: 1518
#Unit 4. Cell Communication and Cell Signaling
Following statements are regarding to the some cancers harbor characteristic chromosome alterations. Chronic myelogenous leukemia (CML), a common leukemia in humans, was found to be associated with the Philadelphia chromosome.
A. Philadelphia chromosome is generated by a translocation between chromosomes 22 and 9. The two chromosomes exchange their terminal regions, which leads to a characteristic alteration in the size of chromosome 9.
B. At the breakpoint of this translocation, a new fusion protein, the BCR-ABL fusion, is generated.
C. The BCR-ABL fusion protein is a constitutively active kinase that phosphorylates multiple signal-transducing proteins.
D. If this translocation occurs in a hematopoietic cell in the bone marrow, the activity of the chimeric BCR-ABL oncogene dephosphorylate proteins thereby activating many intracellular signal-transducing proteins.
Which of the following statements are incorrect?
#Question id: 23143
#Unit 13. Methods in Biology
#Question id: 5042
#Unit 5. Developmental Biology
Which one of the following set of Yamanaka factors can be used to regained the pluripotency of somatic cells in mammals?
#Question id: 907
#Unit 1. Molecules and their Interaction Relevant to Biology
Thermodynamics of protein folding is depicted as a free energy vs folding process:
Choose the correct match for regions mentioned in the figure
A. |
1. Molten globule |
B. |
2. Unfolded |
C. |
3. Transition state |
D. |
4. Folded |
#Question id: 10214
#Unit 6. System Physiology – Plant
LHCII, one of the membrane-bound antenna pigment proteins, which can be phosphorylated and non-phosphorylated by a specific kinase present in thylakoid membrane. Which of the following statements are NOT TRUE ?