Practice Questions

TLS Online TPP Program

#Question id: 12836

The final layer of control that is critical in the regulation of CDKs is a family of proteins known as CDK inhibitors, or CKIs, which bind directly to the cyclin-CDK complex and inhibit its activity. Which of the following function not done by CKIs?

#Unit 2. Cellular Organization

Binding of INK4s to CDK4 and CDK6 blocks their interaction with cyclin D and hence their protein kinase activity.
p27 prevents the premature activation of S phase CDKs during G1.
p21CIP plays an important role in the response of metazoan cells to DNA damage by inhibiting G1/S phase CDKs and S phase CDKs, and thereby blocking entry into or passage through S phase.
During ongoing DNA replication and in response to replication stress (slow DNA replication fork movement or DNA replication fork collapse), the ATR-Chk1 protein kinase cascade phosphorylates and inactivates Cdc25C, thereby preventing the activation of mitotic CDKs and inhibiting entry into mitosis.

More Questions

TLS Online TPP Program

#Question id: 4169

#Unit 3. Fundamental Processes

The first amino acid incorporated into proteins __.

TLS Online TPP Program

#Question id: 824

#Unit 1. Molecules and their Interaction Relevant to Biology

why comparisons of the X-ray structures of hyperthermophilic enzymes with their mesophilic counterparts have failed to reveal any striking differences between them?

TLS Online TPP Program

#Question id: 26347

#Unit 2. Cellular Organization

Which of the following stimulates the formation of the 30 nm fiber

TLS Online TPP Program

#Question id: 12231

#Unit 10. Ecological Principles

Which of the following studies would a community ecologist undertake to learn about competitive interactions?

TLS Online TPP Program

#Question id: 905

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is correct about chaperones