TLS Online TPP Program

#Question id: 12834


How Aurora B and the spindle assembly checkpoint pathway collaborate during every cell cycle to accurately attach every single pair of sister chromatids to the mitotic spindle in the correct, bioriented manner?

#Unit 2. Cellular Organization
  1. Aurora B phosphorylate microtubule-binding component of the kinetochore, the Ndc80 complex, leads to the generation of attached kinetochores, which are recognized by the spindle assembly checkpoint pathway.
  2. Aurora B phosphorylate microtubule-binding component of the kinetochore, the Ndc80 complex, leads to the generation of unattached kinetochores, which are recognized by the spindle assembly checkpoint pathway.
  3. Aurora B dephosphorylate microtubule-binding component of the kinetochore, the Ndc80 complex, leads to the generation of unattached kinetochores, which are recognized by the spindle assembly checkpoint pathway.
  4. Aurora B ubiquitinylates microtubule-binding component of the kinetochore, the Ndc80 complex, leads to the degradation of unattached kinetochores, which are recognized by the spindle assembly checkpoint pathway.
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TLS Online TPP Program

#Question id: 15779

#Unit 5. Developmental Biology

During stem cell regulation extracellular mechanisms leading to intracellular changes that regulate stem cell behaviour. Which of the following is not consider as extracellular mechanisms for stem cell regulation?

TLS Online TPP Program

#Question id: 2065

#Unit 2. Cellular Organization

Which of the following are least likely to diffuse through the phospholipid bilayer of a cell membrane?

TLS Online TPP Program

#Question id: 1386

#Unit 4. Cell Communication and Cell Signaling

The ability of a population of fibroblasts to migrate along the surface of a tissue culture dish depends on adhesion between the cell surface and the extracellular matrix molecules coating the dish. The dish is coated with laminin, and the only cell-surface protein capable of binding laminin is a cell-adhesion protein called an integrin. Integrins are integral plasma-membrane proteins that function as heterodimers. Under these conditions the rate at which a fibroblast can migrate along the laminin coated culture dish is proportional to the strength of adhesion between the cell and the laminin substrate. The table below lists the rate of cell migration observed for fibroblasts genetically engineered to generate the indicated phenotypes. One explanation for the effect of overexpression of the cytoplasmic domain of the integrin beta subunit is that this domain normally functions to bind a cytoplasmic factor necessary for integrin function. Which of the following would be the most informative experiment to identify the cytoplasmic factor?

TLS Online TPP Program

#Question id: 12234

#Unit 10. Ecological Principles

All of the following have been used by plants to avoid being eaten except

TLS Online TPP Program

#Question id: 3052

#Unit 2. Cellular Organization

How many average CFU will form on petriplate if 0.1ml sample plating from 104 diluted sample (original sample contain 3x10^7 bacteria per ml)