Mitotic CDK complexes are maintained in an inactive state through inhibitory phosphorylation of the CDK subunit. Two highly conserved tyrosine and threonine residues in mammalian CDKs are subject to regulated phosphorylation.

Gene	Mutant phenotypes
A. Wee1	i. the cell does not divide but continues to grow
B. CAK kinase	ii. mitotic cyclins are inactivated
C. cdc25 phosphatase	iii. premature entry into mitosis

The following table enlists genes and phenotypes observed on mutation of these genes but not correctly matched. Which one of the following combinations is correctly matched ?

#Question id: 4659

#Unit 3. Fundamental Processes

Many bacterial responses are controlled by two component regulatory systems. What will happen at the high concentration of glutamine and at the low concentration of glutamine?

a) At high concentrations glutamine binds to a sensor domain of NtrB conformational change in the protein that inhibits its histidine kinase activity

b) NtrC phosphorylation takes place causes a conformational change in NtrC that unmasks the NtrC DNA-binding domain so that it can bind to the glnA enhancers

c) At the same time, the regulatory domain of NtrC blocks its DNA-binding domain from binding the glnA enhancers

d) At low concentrations of glutamine dissociates from the sensor domain in the NtrB protein, leading to activation of a histidine kinase transmitter domain

Which of the following given combination is correct?

#Question id: 4561

#Unit 3. Fundamental Processes

Which factor recruits capping enzyme?

#Question id: 4560

#Unit 3. Fundamental Processes

TFIIH general is a general transcription factor phosphorylates the CTD multiple times on heptapeptide sequence such as

#Question id: 4559

#Unit 3. Fundamental Processes

The 5’Cap is added to the eukaryotic nascent RNAs shortly after

#Question id: 4558

#Unit 3. Fundamental Processes

Classes of RNA transcribed by the three eukaryotic nuclear RNA Polymerase;

 Match the following correct combination given above combinations;

#Question id: 4557

#Unit 3. Fundamental Processes

In eukaryotic transcription RNA polymerase II is transcribed