Cell cycle is regulated by master regulators (cyclin and CDKs). In vertebrates, G1 CDK activity rises during G1 and is stimulated by the presence of growth factors. When signaling from growth factors is sustained, the resulting cyclin D–CDK4/6 complexes begin phosphorylating Rb, releasing some E2F, which stimulates transcription of the genes encoding cyclin E, CDK2, and E2F itself. In a particular cell type there is a mutation in Rb such that it cannot be phosphorylated. What will be the correct expression pattern of cyclin E in these cells after mitotic stimulation?

TLS Online TPP Program

#Question id: 1378

#Unit 4. Cell Communication and Cell Signaling

Which of the following apply to fibronectins? Please select all that apply.

a) They are disulphide linked dimers, with each polypeptide composed of a number of binding domains joined together by short flexible segments.

b) They have an essential role in linking the extracellular matrix to its underlying cells.

c) Like integrins, fibronectins are directly connected to the cytoskeleton.

d) They participate in 'inside out' and 'outside in' signalling mechanisms.

TLS Online TPP Program

#Question id: 19344

#Unit 12. Applied Biology

What is the full form of PSA as a type of cancer bioelements ?

TLS Online TPP Program

#Question id: 9212

#Unit 9. Diversity of Life Forms

Burning fossil fuels releases oxides of sulfur and nitrogen. These air pollutants can be responsible for ________.

TLS Online TPP Program

#Question id: 11194

#Unit 7. System Physiology – Animal

The "threshold" potential of a membrane is the ________.

TLS Online TPP Program

#Question id: 11119

#Unit 7. System Physiology – Animal

Which one of the following is NOT true of inspiration