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TLS Online TPP Program

#Question id: 2978

The most important regulatory control that restricts cyclins to the appropriate cell cycle stage is ubiquitin mediated, proteasome-dependent protein degradation. Which of the following statement is incorrect regarding to the degradation of protein?

#Unit 2. Cellular Organization

  1. SCF and APC/C are multisubunit ubiquitin-protein ligases that belong to the RING finger family of ubiquitin protein ligases which ensure that the cell cycle engine is driven forward and that cells cannot “go backward” in the cell cycle.

  2. SCF recognizes its substrates only when they are phosphorylated.

  3. The substrate specificity of active, dephosphorylated APC/C is determined in part by its association with one of two related substrate targeting factors called Cdc20 and Cdh1.

  4. The substrates of APC/C contain recognition motifs known as destruction box which is lysine rich.

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TLS Online TPP Program

#Question id: 19226

#Unit 12. Applied Biology

A systematic examination of the conditions that are used in Agrobacterium-mediated plant transformation revealed that a hormone that significantly decreased the transfer of genes to plant genomes. It is
TLS Online TPP Program

#Question id: 19223

#Unit 12. Applied Biology

Based on the DNA sequence of a commonly used binary vector some example are
1. pBIN19
2. pCB301
3. pBR322
Which of the following above statements are correct?
TLS Online TPP Program

#Question id: 19216

#Unit 12. Applied Biology

Agrobacterium respond to which plant phenolic compounds which are excreted by susceptible wounded plants.
1. Toluene
2. Acetosyringone 
3. Hydroxyacetosyringon
Which of the option have incorrect statement?
TLS Online TPP Program

#Question id: 17085

#Unit 12. Applied Biology

Spontaneous cell fusion occurs at a very low rate. Enhanced fusion can be done by 
1. Sendai virus 
2. Polyethylene glycol
3. Ficol
4. Phenol red
Which of the above mentioned can be used for fusion experiments?
TLS Online TPP Program

#Question id: 17076

#Unit 12. Applied Biology

The various advantages of serum-free media could be
1. Improved reproducibility of results from different laboratories
2. Easier downstream processing of products from cultured cells
3. Biassays are free from interference due to serum proteins
4. They permit selective culture of diffrentiated cell types from the heterogeneous cultures
Which of the statements are true?
TLS Online TPP Program

#Question id: 16492

#Unit 12. Applied Biology

Upstream elements on the other hand regulates the activity of gene action are
A. Enhancer sequences
B. Silencer sequences
C. Termination sequences
D. Signal sequences
Mark the option with correct combination