#Question id: 12070
#Unit 7. System Physiology – Animal
#Question id: 5014
#Unit 11. Evolution and Behavior
Following geological time period and major evolutionary event?
I. Devonian A. Gymnosperms dominant
II. Jurassic B. Amphibians diversify; first reptiles
III. Carboniferous C. Mammals appear
IV. Triassic D. Seed plants appear
#Question id: 520
#Unit 1. Molecules and their Interaction Relevant to Biology
Enzymes that catalyze the same reaction are called ________.
#Question id: 5709
#Unit 8. Inheritance Biology
What is probability of couple where male is karyotypically normal and the female in pericentric inversion in heterozygous condition produced child with disability if 50% chance of crossing over takes placed within pericentric inversion. (Note: Duplication and deletion in gamete will results in disability)
#Question id: 15306
#Unit 4. Cell Communication and Cell Signaling
The transformation of a normal cell to a cancer cell is accompanied by the loss of function of one or more tumor‐suppressor genes. High‐throughput sequencing studies have identified hundreds of genes that are implicated as tumor suppressors in humans. Some of the better characterized genes;
Gene |
Primary tumor |
Proposed function |
i) APC |
Colorectal |
Binds β
‐catenin acting as transcription factor |
ii) BRCA1 |
Breast |
DNA repair |
iii) MSH2, MLH1 |
Melanoma, pancreatic |
p16: Cdk inhibitor ARF: stabilizes p53 |
iv) E‐Cadherin |
Breast, colon |
Cell adhesion molecule |
v) INK4a |
Colorectal |
Mismatch repair |
vi) NF1 |
Neurofibromas |
Activates GTPase of Ras |
Choose incorrect matching regarding tumor‐suppressor genes/primary tumor/proposed functions; |