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TLS Online TPP Program

#Question id: 13159

How signaling is involved in ensuring that yeast cells fuse only with cells of the opposite mating type?

#Unit 4. Cell Communication and Cell Signaling
  1. The two cells of opposite mating type (a and alpha) each secrete a certain signaling molecule, which can only be bound by receptors carried on cells of the opposite mating type. Thus, the a mating factor cannot bind to another a cell and cause it to grow toward the first a cell. Only an alpha cell can “receive” the signaling molecule and respond by directed growth.
  2. The two cells of opposite mating type (a and alpha) each secrete a certain signaling molecule, which can only be bound by receptors carried on cells of the same mating type. Thus, the a mating factor can bind to another a cell and cause it to grow toward the first a cell.
  3. The two cells of opposite mating type (a and alpha) each proteins attached to the plasma membrane of one cell can interact directly with cell-surface receptors on adjacent cells. Thus, the a mating factor can directly bind to another a cell and cause it to grow.
  4. The two cells of opposite mating type (a and alpha) each respond to substances that they themselves release.
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TLS Online TPP Program

#Question id: 4660

#Unit 3. Fundamental Processes

Two-component system regulating response to low Gln,

a) Glutamine dissociates from the sensor domain in the NtrB protein, leading to activation of a histidine kinase transmitter domain in NtrB

b) glutamine binds to a sensor domain of NtrB, causing a conformational change in the protein that inhibits its histidine kinase activity, the regulatory domain of NtrC blocks its DNA-binding domain from binding the glnA enhancers.

c) Activated transmitter domain of NtrB that transfers the γ-phosphate of ATP to a histidine residue (H), this phosphohistidine then transfers the phosphate to an aspartic acid residue (D) in the NtrC protein

d) This causes a conformational change in NtrC that unmasks the NtrC DNA-binding domain so that it can bind to the glnA enhancers

Which of the following combination is correct?
TLS Online TPP Program

#Question id: 4659

#Unit 3. Fundamental Processes

Many bacterial responses are controlled by two component regulatory systems. What will happen at the high concentration of glutamine and at the low concentration of glutamine?

a) At high concentrations glutamine binds to a sensor domain of NtrB conformational change in the protein that inhibits its histidine kinase activity

b) NtrC phosphorylation takes place causes a conformational change in NtrC that unmasks the NtrC DNA-binding domain so that it can bind to the glnA enhancers

c) At the same time, the regulatory domain of NtrC blocks its DNA-binding domain from binding the glnA enhancers

d) At low concentrations of glutamine dissociates from the sensor domain in the NtrB protein, leading to activation of a histidine kinase transmitter domain

Which of the following given combination is correct?
TLS Online TPP Program

#Question id: 4561

#Unit 3. Fundamental Processes

Which factor recruits capping enzyme?
TLS Online TPP Program

#Question id: 4560

#Unit 3. Fundamental Processes

TFIIH general is a general transcription factor phosphorylates the CTD multiple times on heptapeptide sequence such as
TLS Online TPP Program

#Question id: 4559

#Unit 3. Fundamental Processes

The 5’Cap is added to the eukaryotic nascent RNAs shortly after
TLS Online TPP Program

#Question id: 4558

#Unit 3. Fundamental Processes

Classes of RNA transcribed by the three eukaryotic nuclear RNA Polymerase;

                    Polymerase

             RNA Transcribed     

A. RNA polymerase I                   

i) tRNAs, 5S rRNA, snRNA, U6, 7S RNA

B. RNA polymerase II

ii) Pre-rRNA 28S, 18SrRNA,  5.8SrRNAs

C. RNA polymerase III

iii) mRNA, snRNAs, siRNAs, miRNAs

 Match the following correct combination given above combinations;