Practice Questions

TLS Online TPP Program

#Question id: 1262

Although MAP kinase is often activated in multicellular animals by RTKs or cytokine receptors, signaling from other receptors can activate MAP kinase in other eukaryotic cells. we consider the mating pathway in the yeast S. cerevisiae, a well-studied example of a MAP kinase cascade linked to G protein–coupled receptors (GPCRs). Which of the following statement is incorrect?

#Unit 4. Cell Communication and Cell Signaling

An a haploid cell secretes the a mating factor and has GPCRs for the α factor on its cell surface; an α cell secretes the α factor and has GPCRs for the a factor. Thus each type of cell recognizes the mating factor produced by the opposite type.
Ligand binding and dissociation of the G protein subunits, the membrane-tethered Gβγ subunit binds the Ste5 scaffold to the plasma membrane.
Gβγ also activates Cdc24, a GAP for the Ras-like protein Cdc42; the active, GTP-bound Cdc42, in turn, binds to and activates the Ste20 kinase.
Ste20 then phosphorylates and activates Ste11, which is analogous to Raf and other mammalian MEK kinase (MEKK) proteins. Ste20 thus serves as a MAPKKK kinase.

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TLS Online TPP Program

#Question id: 5650

#Unit 5. Developmental Biology

Thalidomide, now banned for use as a sedative during pregnancy, was used in the early 1960s by many women in their first trimester of pregnancy. Some of these women gave birth to children with limb and organ deformities, suggesting that the drug most likely influenced ________.

TLS Online TPP Program

#Question id: 5649

#Unit 5. Developmental Biology

From earliest to latest, the overall sequence of early development proceeds in which of the following sequences?

TLS Online TPP Program

#Question id: 5648

#Unit 5. Developmental Biology

Use the following information to answer the question. In order to test how sea urchin sperm bind to eggs, scientists isolated the egg receptor protein that binds to the sperm acrosomal protein called bindin. Plastic beads were coated with egg receptor for bindin (ERB1) from eggs of the sea urchin Strongylocentrotus purpuratus, and then the beads mixed with sperm from S. purpuratus or from the related species, S. franciscanus. The researchers counted how many sperm were bound to each bead. The results are shown in the graph below. Treatments:

A: S. purpuratus sperm mixed with S. purpuratus ERB1 beads

B: S. purpuratus sperm mixed with beads containing no ERB1 protein

C: S. franciscanus sperm mixed with S. purpuratus ERB1 beads

D: S. franciscanus sperm mixed with beads containing no ERB1 protein

What is a broader implication from the observations of the experiment?

TLS Online TPP Program

#Question id: 5035

#Unit 5. Developmental Biology

A fertilized egg is called a:

TLS Online TPP Program

#Question id: 5036

#Unit 5. Developmental Biology