Following statements are regarding to the phosphoinositide pathway.

A. many activated RTKs and cytokine receptors initiate phosphoinositide pathway by recruiting the enzyme phosphatidylinositol-3 kinase (PI-3 kinase) to the membrane.

B. PI-3 kinase adds a phosphate to the 3′ carbon in one of two separate phosphatidylinositol substrates, leading to formation of two phosphatidylinositol 3-phosphates: PI(3,4)P2 or I(3,4,5)P3

C. PI-3 kinase pathway can trigger cell division and prevent apoptosis, thus ensuring cell survival by the activation of PKB.

D. Activated PKB phosphorylates FOXO3a, which induces the expression of several antiapoptotic genes.

Which of the following combination is correct?

TLS Online TPP Program

#Question id: 19806

#Unit 12. Applied Biology

Several approaches have been used to engineer plants for virus resistance, which are as follows:

(1) coat protein gene 

(2) ribozyme-mediated protection

(3) defective viral genome

(4) antisense RNA approach

Which of the following above statements are correct?

TLS Online TPP Program

#Question id: 19805

#Unit 12. Applied Biology

Some strains of B. thuringiensis produce vegetative insecticidial proteins known as

TLS Online TPP Program

#Question id: 19804

#Unit 12. Applied Biology

Insecticidal protein gene from the Streptomycesis taken and transformed tobacco plants to get resistance with

TLS Online TPP Program

#Question id: 19803

#Unit 12. Applied Biology

Cowpea trypsin inhibitor (cpti), serine protease inhibitor (aprotinin), are all used as alternative insecticidal proteins. They are inhibitors of 

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#Question id: 19802

#Unit 12. Applied Biology

The low expression level of cry genes seems to be due to the presence in them of sequences not commonly found in plant coding regions. Such as

(1) Localized A+T-rich regions resembling plant intrans 

(2) 18 potential plant polyadenylation signal sequences 

(3) 13 ATTTA sequences, which destabilize mRNA

(4) Codons that are rarely used in plants

Which of the above statements are correct?                

TLS Online TPP Program

#Question id: 19801

#Unit 12. Applied Biology

The inheritance of resistance to Cry proteins in insect populations is usually _______ and is governed by one or few major genes