Scaffolds for MAP kinase pathways are well documented in yeast, fly, and worm cells, but their presence in mammalian cells has been difficult to demonstrate. Perhaps the best documented scaffold protein in metazoans is Ksr (kinase suppressor of Ras).

A. Ksr functions as a molecular scaffold by binding several signaling components of the MAP kinase cascade, including both MEK and MAP kinase; and thus can enhance MAP kinase activation by regulating the efficiency of these interactions.

B. Ksr function as a protein kinase which constitutive activate RTK signalling pathway.

C. Ksr function as a receptor proteins which inhibits RTK signalling pathway.

D. Ksr function as a protein phosphatase which inhibits RTK signalling pathway.

Which of the following statement is correct about Ksr?

TLS Online TPP Program

#Question id: 348

#Unit 1. Molecules and their Interaction Relevant to Biology

Sulfur is in the same column of the periodic table as oxygen, but has electronegativity similar to carbon. Compared to water molecules, molecules of H2S will ________.

TLS Online TPP Program

#Question id: 26948

#Unit 10. Ecological Principles

Calculate the population doubling time, if given the intrinsic rate of increase is 1.2?

TLS Online TPP Program

#Question id: 5229

#Unit 11. Evolution and Behavior

Two eukaryotic proteins have one domain in common but are otherwise very different. Which of the following processes is most likely to have contributed to this phenomenon?

TLS Online TPP Program

#Question id: 11563

#Unit 7. System Physiology – Animal

Hormones secreted by the posterior pituitary gland are made in the ________.

TLS Online TPP Program

#Question id: 7266

#Unit 5. Developmental Biology

After brief examination of the evolution of the tetrapod limb, from fish fins to human hands, has hopefully illuminated the importance of Hox gene regulation during limb development. Hox genes are critical for: