The ability of a population of fibroblasts to migrate along the surface of a tissue culture dish depends on adhesion between the cell surface and the extracellular matrix molecules coating the dish. The dish is coated with laminin, and the only cell-surface protein capable of binding laminin is a cell-adhesion protein called an integrin. Integrins are integral plasma-membrane proteins that function as heterodimers. Under these conditions the rate at which a fibroblast can migrate along the laminin coated culture dish is proportional to the strength of adhesion between the cell and the laminin substrate. The table below lists the rate of cell migration observed for fibroblasts genetically engineered to generate the indicated phenotypes.

 Which of the following is the most likely explanation for failure of overexpression of the integrin alpha subunit to alter the rate of fibroblast migration?

#Question id: 26488

#Unit 3. Fundamental Processes

rRNA are encoded by two type of RNA pol. RNA pol I and RNA pol III in which 5.8s rRNA is encodes by …………. While 5s rRNA encoded by …

#Question id: 19821

#Unit 12. Applied Biology

The incompatible reaction is found in obligate parasites, and is associated with hypersensitive response of the host triggered by certain unique molecules called 

#Question id: 12957

#Unit 10. Ecological Principles

#Question id: 22950

#Unit 5. Developmental Biology

#Question id: 5685

#Unit 5. Developmental Biology

Human sperm are allowed to fertilize ova having non- functional ovastacin. The following possibilities may be of significance in the fusion of these gametes:

A.        The sperms will not fertilize ova.

B.        The sperms will bind and penetrate the zona pellucida but will not be able to fuse with ovum membrane.

C.        ZP2 will not be clipped by cortical granule protease.

D.        CD9 protein of egg membrane microvilli will not be able to interact sperm membrane proteins in the absence of ovastacin.

E.         Polyspermy may occur frequently.

Which combination of statements represent the outcome of the above event?