TLS Online TPP Program

#Question id: 1385


The ability of a population of fibroblasts to migrate along the surface of a tissue culture dish depends on adhesion between the cell surface and the extracellular matrix molecules coating the dish. The dish is coated with laminin, and the only cell-surface protein capable of binding laminin is a cell-adhesion protein called an integrin. Integrins are integral plasma-membrane proteins that function as heterodimers. Under these conditions the rate at which a fibroblast can migrate along the laminin coated culture dish is proportional to the strength of adhesion between the cell and the laminin substrate. The table below lists the rate of cell migration observed for fibroblasts genetically engineered to generate the indicated phenotypes.

 Which of the following is the most likely explanation for failure of overexpression of the integrin alpha subunit to alter the rate of fibroblast migration?

#Unit 4. Cell Communication and Cell Signaling
  1. The integrin alpha subunit is not required for integrin function.

  2. The integrin alpha subunit cannot function without a beta subunit.

  3. The integrin alpha subunit binds a cytoplasmic protein factor necessary for integrin function.

  4. The integrin alpha subunit alone is functional, but the cell proteolytically destroys the excess integrin alpha subunits.

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TLS Online TPP Program

#Question id: 12591

#Unit 10. Ecological Principles

A community's actual evapotranspiration is a reflection of

TLS Online TPP Program

#Question id: 13191

#Unit 10. Ecological Principles

Which of the following statements about circadian rhythms is correct?

TLS Online TPP Program

#Question id: 13190

#Unit 10. Ecological Principles

During the evolution of life on Earth, the photosynthetic organisms initially responsible for raising atmospheric oxygen concentrations from less than 1 percent to about 20 percent were

TLS Online TPP Program

#Question id: 13189

#Unit 10. Ecological Principles

The relative abundance of C plant species increases with latitude because of the associated temperature gradient. A study in North America found that at  42°  North,  C3  plants  become more  abundant than  C4  plants. Given  an  increase in  mean global  temperatures by  10°C and no  other changes in  environmental conditions,  the latitude at which C3 plants become more abundant:

TLS Online TPP Program

#Question id: 13188

#Unit 10. Ecological Principles

The following figure is a model of seedling establishment as a function of distance from a parent tree. Initial seed density measures the number of seeds falling to the ground. Seed survivorship measures the proportion of seeds that survive to the adult stage at each distance


Which of the following factors is most likely to generate the seed survivorship curve shown? 

TLS Online TPP Program

#Question id: 13187

#Unit 10. Ecological Principles

The following figure is a model of seedling establishment as a function of distance from a parent tree. Initial seed density measures the number of seeds falling to the ground. Seed survivorship measures the proportion of seeds that survive to the adult stage at each distance


Which of the following factors is most likely to generate the seed density curve shown?