Which of the following apply to fibronectins? Please select all that apply.

a) They are disulphide linked dimers, with each polypeptide composed of a number of binding domains joined together by short flexible segments.

b) They have an essential role in linking the extracellular matrix to its underlying cells.

c) Like integrins, fibronectins are directly connected to the cytoskeleton.

d) They participate in 'inside out' and 'outside in' signalling mechanisms.

TLS Online TPP Program

#Question id: 23179

#Unit 13. Methods in Biology

In order to observe FRET two flurophores must be in close proximity of about 10nm distance. Given below are few flurorescent molecules.

1. YFP

2. RFP

3. GFP

4. CFP

Which option below contains correct combination of flurorescent molecules that can give FRET?

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#Question id: 11475

#Unit 7. System Physiology – Animal

Rods exposed to light will ________.

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#Question id: 12076

#Unit 7. System Physiology – Animal

Furosemide (Lasix) is a diuretic that also produces natriuresis. Which of the following is an undesirable side effect of furosemide due to its site of action on the renal tubule?

TLS Online TPP Program

#Question id: 23415

#General Aptitude

Montreal protocol is related to

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#Question id: 15153

#Unit 8. Inheritance Biology

In this problem we will explore some of the many ways that mutations in two different genes can interact to produce different Mendelian ratios. Consider a hypothetical insect species that has red eyes. Imagine mutations in two different unlinked genes that can, in certain combinations, block the formation of red eye pigment yielding mutants with white eyes. In principle, there are two different possible arrangements for two biochemical steps responsible for the formation of red eye pigment. The two genes might act in series such that a mutation in either gene would block the formation of red pigment. Alternatively, the two genes could act in parallel such that mutations in both genes would be required to block the formation of red pigment.

Further complexity arises from the possibility that mutations in either gene that lead to a block in enzymatic activity could be either dominant or recessive. If the crosses is made between a wild type insect with red eyes and a true breeding white eyed strain with mutations in both genes. Such considerations yield the Pathways in parallel with recessive mutations in both genes, determine the phenotype of the F1 progeny and the expected phenotypic ratio of red to white eyed insects in the F2.