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TLS Online TPP Program

#Question id: 15364

In normal cells, FOS and MYC mRNAs and the proteins they encode are intrinsically unstable and degrade rapidly after the genes are transcribed, Conversion of the MYC proto-oncogene into an oncogene can occur by different mechanisms, Other members of this protein set include MAD, MAX, and MNT, choose incorrect statement regarding this,

#Unit 4. Cell Communication and Cell Signaling
  1. MYC-MAX dimers regulate genes that control proliferation, such as cyclins. 
  2. MAD and MNT work with the SIN3 co-repressor protein to bring in histone deacetylases that help to block transcription.
  3. MAD proteins inhibit MYC proteins, which has led to an interest in using MAD proteins, or drugs that stimulate MAD proteins, to rein in excessive MYC activity that contributes to tumor formation.
  4. MYC protein complexes affect transcription by recruiting chromatin-modifying complexes containing histone deacetyl transferases.
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TLS Online TPP Program

#Question id: 12218

#Unit 7. System Physiology – Animal

The control of gastric acid secretion in response to a meal involves several events that take place over a 4- or 5-hr period following the meal. These events include
(1) a decrease in the pH of the gastric contents,
(2) an increase in the rate of acid secretion,
(3) a decrease in the rate of acid secretion, and
(4) an increase in the pH of the gastric contents. Which of the following best describes
the correct temporal order of events over a 4- or 5-hr period following a meal?
TLS Online TPP Program

#Question id: 12217

#Unit 7. System Physiology – Animal

Cystic fibrosis is the most common cause of pancreatitis in children. Which of the following best explains the mechanism of cystic fibrosis–induced pancreatitis?
TLS Online TPP Program

#Question id: 12216

#Unit 7. System Physiology – Animal

Gastric emptying is regulated to ensure the chyme enters the duodenum at an appropriate rate. Which of the following factors promotes gastric emptying?
TLS Online TPP Program

#Question id: 12215

#Unit 7. System Physiology – Animal

Damage to the gastric mucosal barrier is a forerunner of gastric ulcer. Which of the following can both damage the gastric mucosal barrier and stimulate gastric acid secretion?
TLS Online TPP Program

#Question id: 12214

#Unit 7. System Physiology – Animal

A 53-year-old man with a recurrent history of ulcer disease associated with diarrhea and a strong family history of duodenal ulcer disease is suspected of having Zollinger-Ellison syndrome (gastrinoma). Secretin (2 units/kg) was given as a rapid intravenous injection to test for gastrinoma. Which of the following results would support the existence of gastrinoma following secretin administration?
TLS Online TPP Program

#Question id: 12213

#Unit 7. System Physiology – Animal

The gastric phase of gastric secretion accounts for about 60% of the acid response to a meal. Which of the following can virtually eliminate the secretion of acid during the gastric phase?