TLS Online TPP Program

#Question id: 15364


In normal cells, FOS and MYC mRNAs and the proteins they encode are intrinsically unstable and degrade rapidly after the genes are transcribed, Conversion of the MYC proto-oncogene into an oncogene can occur by different mechanisms, Other members of this protein set include MAD, MAX, and MNT, choose incorrect statement regarding this,

#Unit 4. Cell Communication and Cell Signaling
  1. MYC-MAX dimers regulate genes that control proliferation, such as cyclins. 
  2. MAD and MNT work with the SIN3 co-repressor protein to bring in histone deacetylases that help to block transcription.
  3. MAD proteins inhibit MYC proteins, which has led to an interest in using MAD proteins, or drugs that stimulate MAD proteins, to rein in excessive MYC activity that contributes to tumor formation.
  4. MYC protein complexes affect transcription by recruiting chromatin-modifying complexes containing histone deacetyl transferases.
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TLS Online TPP Program

#Question id: 4892

#Unit 8. Inheritance Biology

The RFLP pattern for this locus, obtained by hybridization using a probe internal sites, from family is shown below: Based on the above profile, what is the nature of the genetic disorder?

TLS Online TPP Program

#Question id: 4891

#Unit 8. Inheritance Biology

plantlike organism on the planet Pandora can have three recessive genetic traits: bluish leaves, due to an allele (a) of gene A; a feathered stem, due to an allele (b) of gene B; and hollow roots due to an allele (c) of gene C. The three genes are linked and recombine. A geneticist performed a testcross with an organism that had been found to be heterozygous for the three recessive traits, and she was able to identify progeny of the following phenotypic distribution (+ = wild type):

 A) Genes are in the order: a-c-b

B) Genes are in the order: a-b-c.

C) Genes are in the order: b-a-c

D) Interference is one

E) Greatest distance between gene a and b

TLS Online TPP Program

#Question id: 4890

#Unit 8. Inheritance Biology

A strain of Neurospora crassa, unable to synthesize the vitamin thiamine (t), is crossed with a strain that cannot synthesize the amino acid arginine (a). What information can be obtained from the resultant frequencies of ascospore patterns?

 A) The two loci (a) and (t) are independent assortment of each other

B) Both genes are closely linked to their respective centromeres.

C) no crossovers occurred between either gene and its centromere.

D) These two gene may reside on different chromosomes.

TLS Online TPP Program

#Question id: 4889

#Unit 8. Inheritance Biology

A three point test cross was carried out in Drosophila melanogaster involving three adjacent incomplete link genes A, C and B arranged in the same order. The distance between A to C is 20 map units (mu) and that between B to C is 10 map. If pure line Drosophila AAbbCC crosses with aaBBcc to produce F1 offspring were allowed to cross with aabbcc result in 1000 offspring, which of the following genotype combination with number is correct?

Genotype

Number

I- Aabbcc

a- 90

II- aabbCc

b-40

III- AaBbCc

c-10

TLS Online TPP Program

#Question id: 4888

#Unit 8. Inheritance Biology

The A locus and the D locus are link with 50 % chance of crossing over observed between them. If Ad/Ad is crossed to aD/aD, and the F1 is test cross, which of the following phenotype is statement is correct?

A) Frequency of recombinant progeny is equal to parental frequency

B) Frequency of recombinant progeny is less than parental frequency

C) Distance between Locus A and B is 50 map unit

D) Distance between Locus A and B is 25 map unit

TLS Online TPP Program

#Question id: 4887

#Unit 8. Inheritance Biology

Flower color gene incompletely link to pollen length gene at 20 map unit, Blue follower is dominant over white flower and long pollen is dominant over short pollen. A plant with Blue flower and short pollen was cross with white flower and long pollen. All F1 offspring display blue flower and long pollen was allowed to cross with white flower and short pollen. What is the percent of progeny showing blue flower and long pollen?