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TLS Online TPP Program

#Question id: 1529

Which of the following statements are true regarding to gain-of-function and loss-of-function mutations with respect to cancer.

#Unit 4. Cell Communication and Cell Signaling

  1. A gain-of-function mutation converts a proto-oncogene into an oncogene. Such mutations are dominant and require alteration of single allele. A loss-of-function mutation occurs in tumor-suppressor genes, abrogating their function in preventing cancer. Such mutations are recessive and require alteration of both alleles.

  2. A gain-of-function mutation converts a proto-oncogene into an oncogene. Such mutations are dominant and require alteration of both alleles. A loss-of-function mutation occurs in tumor-suppressor genes, abrogating their function in preventing cancer. Such mutations are recessive and require alteration of single allele.

  3. A gain-of-function mutation occurs in tumor-suppressor genes. Such mutations are dominant and require alteration of single allele. A loss-of-function mutation converts a proto-oncogene into an oncogene, abrogating their function in preventing cancer. Such mutations are recessive and require alteration of both alleles.

  4. A gain-of-function mutation occurs in tumor-suppressor genes. Such mutations are dominant and require alteration of both alleles. A loss-of-function mutation converts a proto-oncogene into an oncogene, abrogating their function in preventing cancer. Such mutations are recessive and require alteration of single allele.

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TLS Online TPP Program

#Question id: 1249

#Unit 4. Cell Communication and Cell Signaling

As in all G protein–coupled signalling pathways, timely termination of the rhodopsin signalling pathway requires that all the activated intermediates be inactivated rapidly, restoring the system to its basal state, ready for signalling again. Which of the following mechanism does not terminate rhodopsin signalling?
TLS Online TPP Program

#Question id: 14698

#Unit 13. Methods in Biology

A bag has 13 red, 14 green and 15 black balls. The probability of getting exactly 2 blacks on pulling out 4 balls is P1. Now the number of each colour ball is doubled and 8 balls are pulled out.The probability of getting exactly 4 blacks is P2. Then
TLS Online TPP Program

#Question id: 12640

#Unit 6. System Physiology – Plant

Plant species produce a which type of  defensive proteins that bind to carbohydrates or carbohydrate-containing proteins. After being ingested by an herbivore, that bind to the epithelial cells lining the digestive tract and interfere with nutrient absorption
TLS Online TPP Program

#Question id: 23925

#General Aptitude

1 metric ton of average coal in energy terms is equivalent to:
TLS Online TPP Program

#Question id: 5721

#Unit 8. Inheritance Biology

There is paracentric inversion heterozygote ABCDEFG/ABFEDCG involved in double recombination during meiosis I within inverted region result in

A. dicentric and an acentric chromosome in meiosis I as the chiasmata get terminated.

B. appearance of deletion in both the cross over product

C. all gamete are viable

D. nonviable gametes from crossover products.

Which of the above statements are correct?