Following statements are regarding to apoptosis.

A. In the worm apoptotic pathway, CED-3 (caspase-9 in mammals) is a protease required to destroy cell components during apoptosis.

B. CED-4 (Apaf-1) was able to accelerate the autoproteolytic cleavage and activation of purified CED-9

C. Once EGL-1 causes dissociation of the CED-4/CED-9 complex, the released CED-4 dimer joins with three other CED-4 dimers to make an octamer, which then activates CED-3

D. Many apoptotic stimuli lead to damage of the outer mitochondrial membrane, causing release into the cytosol of several proteins that stimulate apoptosis. In particular, cytochrome c released from mitochondria activates Apaf-1, which in turn activates caspase-3 and 7.

Which of the following combination is incorrect?

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#Question id: 23154

#Unit 13. Methods in Biology

When the organelles pH is acidic the how the SNARF-1 dye measures this acidity?

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#Question id: 23375

#General Aptitude

Press Council of India is located at:

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#Question id: 325

#Unit 1. Molecules and their Interaction Relevant to Biology

A true statement about hydrophobic interactions is that they:

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#Question id: 16097

#Unit 7. System Physiology – Animal

As ambient temperature increases, heat loss increases by:

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#Question id: 10975

#Unit 7. System Physiology – Animal

A teenaged boy with numerous nosebleeds was referred to a physician for evaluation prior to a minor surgery. His prothrombin time (PT) was 11 sec (11–15 sec normal), partial thromboplastin time (PTT) was 58 sec (25–40 sec normal), and bleeding time was 6.5 min (2–7 min normal). Which of the following is most likely abnormal in this young man?