Tumor-suppressor genes generally encode proteins that in one way or another inhibit cell proliferation. Loss-of-function mutations in one or more of these proliferation inhibitory proteins contribute to the development of many cancers. Prominent among the classes of proteins encoded by tumor-suppressor genes are:

A. Intracellular proteins that regulate or inhibit entry into the cell cycle

B. Receptors or signal transducers for secreted hormones or developmental signals that inhibit cell proliferation

C. Checkpoint pathway proteins that arrest the cell cycle if DNA is damaged

D. Proteins that promote apoptosis

Following genes belongs to the above class-

i. p53

ii. Rb

iii.TGF- β

iv. Caspase 3 and 7

which of the following match is correct?

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#Question id: 757

#Unit 1. Molecules and their Interaction Relevant to Biology

_______________ a bacterial enzyme, uses the energy of ATP hydrolysis to introduce negative supercoiling into DNA hence removing positive supercoiling generated during replication.

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#Question id: 24648

#Unit 10. Ecological Principles

Carnivores are the animals that has the ability to obtaining amino acid by__

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#Question id: 12705

#Unit 8. Inheritance Biology

In Neurospora crasssa, the mutant exhibit poky phenotype, when a female of  poky strain is crossed with a normal strain acting as a male , all progeny individuals shows poky phenotype . however, the reciprocal cross resulted in all normal progeny. These results can be explained on the basis of 

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#Question id: 12970

#Unit 10. Ecological Principles

In deep-sea hydrothermal vents near the Galapagos Islands, bacteria obtain energy by oxidizing hydrogen sulphide released from the vents. Giant tube worms, which lack mouths and digestive systems, harbour the bacteria in their tissues and use them as a source of organic molecules. Clams obtain energy by filtering bacteria directly from the water, and numerous crabs and octopi feed on the clams. In this unique ecosystem, the bactena are playing the role of

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#Question id: 23172

#Unit 13. Methods in Biology

Green fluorescent protein do contains a tripeptide sequence i.e. ser-tyr-gly but it only fluoresce when