Following statements are regarding to the some cancers harbor characteristic chromosome alterations. Chronic myelogenous leukemia (CML), a common leukemia in humans, was found to be associated with the Philadelphia chromosome.

A. Philadelphia chromosome is generated by a translocation between chromosomes 22 and 9. The two chromosomes exchange their terminal regions, which leads to a characteristic alteration in the size of chromosome 9.

B. At the breakpoint of this translocation, a new fusion protein, the BCR-ABL fusion, is generated.

C. The BCR-ABL fusion protein is a constitutively active kinase that phosphorylates multiple signal-transducing proteins.

D. If this translocation occurs in a hematopoietic cell in the bone marrow, the activity of the chimeric BCR-ABL oncogene dephosphorylate proteins thereby activating many intracellular signal-transducing proteins.

Which of the following statements are incorrect?

TLS Online TPP Program

#Question id: 9273

#Unit 6. System Physiology – Plant

In the higher excited state, chlorophyll is extremely unstable; it rapidly gives up some of its energy to the surroundings as heat, and enters the lowest excited state, the excited chlorophyll has four alternative pathways for disposing of its available energy: fluorescence, Heat loss, energy transfer, photochemistry; all process takes place in which wavelength,

TLS Online TPP Program

#Question id: 9272

#Unit 6. System Physiology – Plant

The quantum yield of photosynthesis falls off drastically for far-red light of wavelengths greater than 680 nm, indicating that far-red light alone is inefficient in driving

photosynthesis, this effect is called

TLS Online TPP Program

#Question id: 9270

#Unit 6. System Physiology – Plant

In the lowest excited state, the excited chlorophyll has four alternative pathways for disposing of its available energy which of the statement of alternative pathway would be INCORRECT?

TLS Online TPP Program

#Question id: 9269

#Unit 6. System Physiology – Plant

The distribution of electrons in the excited molecule is somewhat different from the distribution in the groundstate molecule, Absorption of blue light excites the chlorophyll to a higher energy state than absorption of red light because

TLS Online TPP Program

#Question id: 11538

#Unit 7. System Physiology – Animal

Prostaglandins are local regulators whose chemical structure is derived from ________.

TLS Online TPP Program

#Question id: 11539

#Unit 7. System Physiology – Animal

Aspirin and ibuprofen both ________.