TLS Online TPP Program

#Question id: 16955


Stage thymocytes express neither CD4 nor CD8, markers associated with mature T cells. They are therefore called double negative (DN) cells. DN cells first travel to the region under the thymic capsule, a region referred to as the ________, where they proliferate and begin to generate their T-cell receptors. Thymocytes that successfully express TCRs begin to express both CD4 and CD8, becoming double positive (DP) cells, and populate the cortex, the site where most (85% or more) immature T cells are found.

#Unit 4. Cell Communication and Cell Signaling
  1. subcapsular cortex
  2. periphery
  3. cortical thymus
  4. Endosteal niche