TLS Online TPP Program

#Question id: 16148


 Which statement is not true for NKT Cells?

#Unit 4. Cell Communication and Cell Signaling
  1. NKT cells, have received a great deal of recent attention and share features with both conventional T lymphocytes and NK cells.
  2. Like T cells, NKT cells have T-cell receptors (TCRs), and some express CD4. Unlike most T cells, however, the TCRs of NKT cells are not very diverse and recognize specific lipids and glycolipids presented by a molecule related to MHC proteins known as CD1.
  3. Like their innate immune relatives, NK cells, NKT cells have antibody receptors, as well as other receptors classically associated with NK cells. Activated NKT cells can release cytotoxic granules that kill target cells.
  4. they can not also release large quantities of cytokines that can both enhance and suppress the immune response. They appear to be involved in human asthma, but also may inhibit the development of autoimmunity and cancer
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TLS Online TPP Program

#Question id: 5806

#Unit 8. Inheritance Biology

Which of these is NOT a mechanism by which a chromosome rearrangement could affect gene function?

TLS Online TPP Program

#Question id: 5805

#Unit 8. Inheritance Biology

In Himalayan rabbits, the ears, feet, and muzzle are pigmented while the rest of the body is white. This is because they express an enzyme variant that is ineffective at body temperature but functions at the lower temperatures experienced by cells of the extremities. This is an example of:

TLS Online TPP Program

#Question id: 5804

#Unit 8. Inheritance Biology

The gene that is mutated in cases of cystic fibrosis encodes an ion transporter protein normally expressed in the respiratory and digestive tracts along with other locations. Individuals homozygous for the most common mutation in this gene (ΔF508) died at very early ages prior to the advent of advanced medical intervention. Despite this, the mutation exists at relatively high frequency in populations of European descent. One potential explanation is that heterozygotes for such mutations may be relatively immune to the lethal effects of diseases such as typhoid fever. Which statement below is most accurate?

TLS Online TPP Program

#Question id: 5803

#Unit 8. Inheritance Biology

The mutation which causes sickle cell anemia in humans:

TLS Online TPP Program

#Question id: 5802

#Unit 8. Inheritance Biology

A wild type allele:

TLS Online TPP Program

#Question id: 5801

#Unit 8. Inheritance Biology

Which of the following point mutations would be most likely to affect protein function?