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#Question id: 5654


Two human disorders, Prader-Willi syndrome and Angelman syndrome, occur when a small deletion in a specific region of chromosome 15 is contributed by either the father or mother, respectively. Why does this small deletion not behave as a recessive allele for either syndrome, that is, why is its loss not made up for by the good copy of the region on chromosome 15 contributed by the other parent?

#Unit 5. Developmental Biology
  1. This portion of chromosome 15 is invariably mutated, so the other parent contributes recessive alleles that are thus homozygous and perturb development.

  2. The copy of chromosome 15 from the other parent has genes in the region of the deletion that are imprinted, and thus inactive; in the absence of any active copies of these genes, development cannot proceed normally.

  3. The genes in this portion of chromosome 15 are special in that they are required in two copies for normal development, and so the loss of one set does not allow normal development.

  4. Chromosomes with deletions do not go through mitosis correctly, so cell divisions in the embryo result in cells with abnormal numbers of chromosomes, and these cells do not contribute properly to the development of the organism.

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TLS Online TPP Program

#Question id: 4768

#Unit 8. Inheritance Biology

A trait that appears to be dominant in one sex but recessive in the other is called:

TLS Online TPP Program

#Question id: 4785

#Unit 8. Inheritance Biology

One form of white eye is a recessive X-linked gene in Drosophila. From a mating of a heterozygous wild-type Drosophila female with a white-eyed male, what is the probability of wild type offspring?

TLS Online TPP Program

#Question id: 4791

#Unit 8. Inheritance Biology

Body color in mice, YY is a recessive lethal, Yy yellow, yy gray and hair type straight is dominant over fuzzy. A geneticist crosses two yellow mice with heterozygous straight hair. Which the observe ratio is of obtains following progeny?

TLS Online TPP Program

#Question id: 4794

#Unit 8. Inheritance Biology

 Following statement given for a character

A- Characteristics are determined by autosomal genes

B- Inherited according to Mendel’s principles

C-they are different expressivity in males and females

Which of the following having above statements feature?

TLS Online TPP Program

#Question id: 4797

#Unit 8. Inheritance Biology

Non allelic genotype aa governing white phenotype with recessive epistatic over non allelic gene B for red phenotype Which of the following cross would produce 25 % white phenotype in their offspring? 

TLS Online TPP Program

#Question id: 4725

#Unit 8. Inheritance Biology

Ptosis (droopy eyelid) may be inherited as a dominant human trait. Among 30 people who are heterozygous for the ptosis allele, 10 have ptosis and 20 have normal eyelids. What is the penetrance for ptosis?