In drosophila, Physical forces drive invagination of the ventral furrow. Following statements regarding to this process:

A. The cellularized blastoderm will begin to activate higher levels of myosin in the cells at the ventral midline and preferentially at their apical surface.

B. Epithelial adhesions paired with differential activation of dynein and tissue geometry create mechanical constraints that affect the orientation of actomyosin meshworks.

C. The A/P oriented arrays of myosin in the cells at the ventral midline generate tension along the anterior-posterior axis.

D. The combination of tissue geometry and tension of these anterior-to-posterior meshworks cause the tissue to fold outward at a right angle to the anterior-posterior axis, creating a long and narrow ventral furrow.

Which of the following statements are incorrect?

TLS Online TPP Program

#Question id: 24490

#Unit 3. Fundamental Processes

There are three type of Splicing signals 1. Major U2-type or GU-AG introns 2. Minor U12-type or AU-AC introns & 3. Minor U12-type with GU-AG introns (hybrid type), which of the following is responsible for the recognition of branch point sequence UACUAAC?

TLS Online TPP Program

#Question id: 24489

#Unit 3. Fundamental Processes

Two transesterification reactions takes place for 2 exon -1 intron configuration. Choose the correct  statement 

a. First transesterification is always caused by exon 1 -3’OH

b. second transesterification is catalysed variably either by external G or branch point while .

c. First transesterification is catalysed variably either by external G or branch point while 

d. second transesterification is always caused by exon 1 -3’OH.

TLS Online TPP Program

#Question id: 24464

#Unit 3. Fundamental Processes

rRNA are encoded by two type of RNA pol. RNA pol I and RNA pol III in which 5.8s rRNA is encodes by …………. While 5s rRNA encoded by ……

TLS Online TPP Program

#Question id: 4350

#Unit 3. Fundamental Processes

Portions of the DNA sequences of normal and mutant b-globin genes are shown. The most plausible explanation for why the indicated mutation (changing an A to a G) results in the disease b-thalassemia is that the mutation

TLS Online TPP Program

#Question id: 4349

#Unit 3. Fundamental Processes

RNA Pol IV and Pol V

TLS Online TPP Program

#Question id: 4122

#Unit 3. Fundamental Processes

RNA Pol uses its active site, in a simple back-reaction, to catalyze the removal of an incorrectly inserted ribonucleotide. This phenomenon known as