In theory, auxin could increase the rate of proton extrusion by two possible mechanisms:

I) H+-ATPase activation

II) H+-ATPase synthesis

a) Auxin involves in the activation of ATP-driven proton-pump (H+-ATPase) indirectly

b) ABPs appear to be able to activate the plasma membrane H+-ATPase in the presence of auxin

c) Activity of the H+- ATPase is repressed by the C-terminal domain of the enzyme, which can block the catalytic site  in absence of auxin

d) The protein is synthesized on the rough endoplasmic reticulum and targeted via the secretory pathway to the plasma membrane

Find out the correct explanation of given mechanisms.

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A female fly, full of fertilized eggs, is swept by high winds to an island far out to sea. She is the first fly to arrive on this island, and the only fly to arrive in this way. Thousands of years later, her numerous offspring occupy the island, but none of them resembles her. There are, instead, several species each of which eats only a certain type of food. None of the species can fly, for their flight wings are absent, and their balancing organs (i.e., halteres) are now used in courtship displays. The male members of each species bear modified halteres that are unique in appearance to their species. Females bear vestigial halteres. The ranges of all of the daughter species overlap. If these fly species lost the ability to fly independently of each other as a result of separate mutation events in each lineage, then the flightless condition in these species could be an example of

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When varying the substrate concentration at a fixed concentration of enzyme it is observed that at low concentrations of substrate the reaction is ________,while at high concentrations of substrate the reaction is ________.