A 55-year-old male patient with hypertension has had his blood pressure reasonably well controlled by administration of a thiazide diuretic. During his last visit (6 months ago) his blood pressure was 130/75 mm Hg and his serum creatinine was 1 mg/100 ml. He has been exercising regularly for the past 2 years, but recently has complained of knee pain and began taking large amounts of a nonsteroidal anti-inflammatory drug. When he arrives at your office, his blood pressure is 155/85 and his serum creatinine is now 2.5 mg/100 ml. Which of the following best explains his increased serum creatinine?

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#Question id: 12382

#Unit 7. System Physiology – Animal

A person with normal body fluid volumes weighs 60 kg and has an extracellular fluid volume of approximately 12.8 L, a blood volume of 4.3 L, and a hematocrit of 0.4; 57% of his body weight is water.

What is the approximate interstitial fluid volume?

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#Question id: 12381

#Unit 7. System Physiology – Animal

 A person with normal body fluid volumes weighs 60 kg and has an extracellular fluid volume of approximately 12.8 L, a blood volume of 4.3 L, and a hematocrit of 0.4; 57% of his body weight is water.

What is the approximate plasma volume?

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#Question id: 12380

#Unit 7. System Physiology – Animal

A person with normal body fluid volumes weighs 60 kg and has an extracellular fluid volume of approximately 12.8 L, a blood volume of 4.3 L, and a hematocrit of 0.4; 57% of his body weight is water. What is the approximate intracellular fluid volume?

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#Question id: 12379

#Unit 7. System Physiology – Animal

A healthy 29-year-old man runs a 10-km race on a hot day and becomes very dehydrated. Assuming that his antidiuretic hormone levels are very high, in which part of the renal tubule is the most water reabsorbed?

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#Question id: 12308

#Unit 7. System Physiology – Animal

 Which of the following statements is correct?

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#Question id: 12307

#Unit 7. System Physiology – Animal

If a person has a kidney transport maximum for glucose of 350 mg/min, a GFR of 100 ml/min, a plasma glucose of 150 mg/dL, a urine flow rate of 2 ml/min, and no detectable glucose in the urine, what would be the approximate rate of glucose reabsorption, assuming normal kidneys?