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TLS Online TPP Program

#Question id: 20271

Nephrogenic diabetes insipidus is treated with thiazide diuretics. The usefulness of thiazide diuretics in treating nephrogenic diabetes insipidus is explained as follows:
a. Thiazide diuretics inhibit Na+ reabsorption in the early distal tubule. By preventing dilution of the urine at that site, the final, excreted urine is less dilute.
b. Thiazide diuretics decrease glomerular filtration rate; because less water is filtered, less water is excreted.
c. Thiazide diuretics, by increasing Na+ excretion, can cause a secondary ECF volume contraction.
Which one of the following combination of above statements is correct?

#Unit 7. System Physiology – Animal
  1. a and b
  2. b and c
  3. a and c
  4. a, b and c
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TLS Online TPP Program

#Question id: 5355

#Unit 8. Inheritance Biology

The characteristics of X-linked inheritance as following statement are correct

A- Reciprocal crosses resulting in different phenotypic ratios in their offspring 

B- Heterozygous females transmit each X-linked allele to approximately half their daughters and half their sons

C- Males that inherit an X-linked recessive allele always exhibit the recessive trait

D-Females that inherit an X-linked recessive allele from male always exhibit the dominant trait

E- Males do not transmit each X-linked allele to their sons
TLS Online TPP Program

#Question id: 5354

#Unit 8. Inheritance Biology

Eye color gene link with X chromosome, If red eye color gene is dominant over white eye color gene. Which of the following genetic cross and their respective offspring is not correlated?

Genetic cross

Phenotype of offspring

1

Heterozygous Red eye female  X   Red eye Male

All male red eye

2

Heterozygous Red eye female  X   white  eye Male 

 Male either red  or white eye

3

Homozygous Red eye female  X   white eye Male 

All female red eye

4

Homozygous Red eye female  X   Red  eye Male

All male red eye

TLS Online TPP Program

#Question id: 5353

#Unit 8. Inheritance Biology

Which of following is not a mode of inheritance, but female parents (I-1) carry only normal allele?

A. X link recessive              b. Autosomal recessive

c. Autosomal dominant      d. X- link dominant
TLS Online TPP Program

#Question id: 5352

#Unit 8. Inheritance Biology

Marriage occurs between individuals III-3 and III-6, what is the probability couple; son would be affected with the trait?
TLS Online TPP Program

#Question id: 5351

#Unit 8. Inheritance Biology

Consider the accompanying pedigree of a rare autosomal recessive disease, PKU. (Assume individual coming from outside that is homozygous for normal allele) What is the probability of child showing trait of A and B individuals?
TLS Online TPP Program

#Question id: 5350

#Unit 8. Inheritance Biology

Which of the following most probable mode of genetic disorder?