ADH has two actions, one on the kidney and the other on vascular smooth muscle, these actions are mediated by different receptors, different intracellular mechanisms, and different secondary messengers.

a. The major action of ADH is to increase the water permeability of principal cells in the late distal tubule and collecting duct.

b. The receptor for ADH on the principal cells is a V2 receptor, which is coupled to adenylyl cyclase via a Gs protein. 

c. The second messenger is cAMP, via phosphorylation steps, directs the insertion of water channels, aquaporin 2 (AQP2), in luminal membranes.

d. The receptor for ADH on the principal cells is a V1 receptor, which is coupled to phospholipase C via Gq protein.

Which one of the following combination of above statements is correct?

TLS Online TPP Program

#Question id: 23596

#Unit 1. Molecules and their Interaction Relevant to Biology

Pointing to Varman, Madhav said, “I am the only son of one of the sons of his father.” How is Varman related to Madhav?

TLS Online TPP Program

#Question id: 23597

#Unit 1. Molecules and their Interaction Relevant to Biology

Introducing a woman, Shashank said, “She is the mother of the only daughter of my son.” How that woman is related to Shashank?

TLS Online TPP Program

#Question id: 23598

#Unit 1. Molecules and their Interaction Relevant to Biology

If A + B means B is the brother of A; A ×B means B is the husband of A; A −B means A is the mother of B and A%B means A is the father of B, which of the following relations shows that Q is the grandmother of T?

TLS Online TPP Program

#Question id: 22017

#Unit 1. Molecules and their Interaction Relevant to Biology

The Hanes plot (devised by Charles Hanes) obtained by using Lineweaver-Burk equation by 

TLS Online TPP Program

#Question id: 653

#Unit 1. Molecules and their Interaction Relevant to Biology

For the enzyme-catalyzed reaction S ~ P, Keq = 5, which of the following curves best represents the change in [S] that occurs with time when S is added to a solution containing the appropriate enzyme?

TLS Online TPP Program

#Question id: 652

#Unit 1. Molecules and their Interaction Relevant to Biology

Two proteins, X and Y, bind to the same ligand, A, with the binding curves shown below. Which of the statement is correct for the graph analysing two proteins?