You have isolated a set of five yeast mutants that form dark red colonies instead of the usual white colonies of wild-type yeast. You cross each of the mutants to a wild-type haploid strain and obtain the results shown below;

What do these results tell you about each of the mutants?

#Question id: 2636

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following events occur when E. coli is starved for tryptophan?

I.  The ribosome translates leader peptide completely

II. Transcription reads through attenuator into trp EDCBA

III. Tryptophanyl tRNA is not formed

IV. A stem loop structure involving regions 3 and 4 is formed at attenuator site

#Question id: 837

#Unit 1. Molecules and their Interaction Relevant to Biology

Increasing order of free energy in unfolded to folded conformation of the proteins, the correct order is,

#Question id: 835

#Unit 1. Molecules and their Interaction Relevant to Biology

The minor clefts and gullies on the sides of the funnel that will be false energy minima, it represents,

#Question id: 1520

#Unit 1. Molecules and their Interaction Relevant to Biology

Following statements are regarding to enzymatic processing of benzo(a)pyrene to a more potent mutagen and carcinogen.

A. Liver enzymes, particularly P-450 enzymes, modify benzo(a)pyrene in a series of reactions, producing 7,8-diol-9,10-epoxide, a highly potent mutagenic species that reacts with DNA primarily at the N2 atom of a guanine base.

B. The adduct, (+)-trans-anti-B(a)P-N2-dG, causes polymerase to insert an A rather than a C opposite the modified G base. Next time the DNA is replicated, a T will be inserted opposite the A, and the mutation will be complete.

C. Potent mutagen majorly causes conversion of guanine (G) to thymine (T) bases, a transition mutation.

D. When this potent mutagen applied to cultured bronchial epithelial cells, activated benzo(a)pyrene induces many mutations, including activating mutations at codons 175, 248, and 273 of the p53 gene.

Which of the following statements are correct?

#Question id: 674

#Unit 1. Molecules and their Interaction Relevant to Biology

Proline is not often found in a-helices of proteins because it

#Question id: 73

#Unit 1. Molecules and their Interaction Relevant to Biology

Match the Variation of Reaction Spontaneity (Sign of ΔG) given in Column I with the Signs of ΔH and ΔS given in column II.