TLS Online TPP Program

#Question id: 15121


Which of the following examples would NOT be consistent with a gene dosage effect?

#Unit 8. Inheritance Biology
  1. Males with one normal allele for the X linked gene dystrophin are unaffected, while females (who shut off one of their two X chromosomes) with one normal allele for dystrophin may be mildly affected with muscular dystrophy.
  2. Flower colour in four-o-clocks seems to be incompletely dominant.
  3. In fruit flies, homozygotes for an allele that produces a small amount of functional protein are severely abnormal but survive to adulthood, while homozygotes for an allele that produces no protein at all die as embryos.
  4. In bels Males normal are haploid while females normally are diploid
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TLS Online TPP Program

#Question id: 1245

#Unit 4. Cell Communication and Cell Signaling

Many PTB-containing proteins act as docking sites for multiple proteins. If these proteins are involved in the RTK signal transduction pathway, they most likely:

TLS Online TPP Program

#Question id: 1244

#Unit 4. Cell Communication and Cell Signaling

Which type of experimental evidence shows that the intrinsic GTPase activity of the Gα subunit is important for terminating effector activation?

TLS Online TPP Program

#Question id: 1243

#Unit 4. Cell Communication and Cell Signaling

One form of receptor desensitization can be mediated by negative feedback involving phosphorylation of the receptor itself by a kinase activated downstream of a second messenger. The phosphorylated receptor likely:

TLS Online TPP Program

#Question id: 1242

#Unit 4. Cell Communication and Cell Signaling

Rhodopsin, a light-sensitive GPCR whose role in vision is dependent on its phosphorylation status, is influenced in part by the protein arrestin.  Which of the following is TRUE with regard to rhodopsin and vision?

TLS Online TPP Program

#Question id: 1241

#Unit 4. Cell Communication and Cell Signaling

Which of the following is a common step in the opening/closing of ion channels by acetylcholine and rhodopsin binding to their receptors?

TLS Online TPP Program

#Question id: 1239

#Unit 4. Cell Communication and Cell Signaling

GTPases serve in many signal transduction pathways and the presence of GTP or GDP dictates whether the pathway is on or off, respectively. Which of the following statements is TRUE regarding guanine nucleotide exchange factors (GEF) and the role in these signaling pathways?