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TLS Online TPP Program

#Question id: 5804

The gene that is mutated in cases of cystic fibrosis encodes an ion transporter protein normally expressed in the respiratory and digestive tracts along with other locations. Individuals homozygous for the most common mutation in this gene (ΔF508) died at very early ages prior to the advent of advanced medical intervention. Despite this, the mutation exists at relatively high frequency in populations of European descent. One potential explanation is that heterozygotes for such mutations may be relatively immune to the lethal effects of diseases such as typhoid fever. Which statement below is most accurate?

#Unit 8. Inheritance Biology

  1. The ΔF508 cystic fibrosis mutation is a beneficial mutation.

  2. The ΔF508 cystic fibrosis mutation is a lethal mutation.

  3. The ΔF508 cystic fibrosis mutation is a conditional mutation.

  4. The ΔF508 cystic fibrosis mutation is a neutral mutation

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TLS Online TPP Program

#Question id: 11481

#Unit 7. System Physiology – Animal

Which of the following sensory receptors is correctly paired with its category?
TLS Online TPP Program

#Question id: 12955

#Unit 7. System Physiology – Animal

Which of the following would tend to decrease GFR by more than 10% in a normal kidney?
TLS Online TPP Program

#Question id: 12954

#Unit 7. System Physiology – Animal

A 55-year-old male patient with hypertension has had his blood pressure reasonably well controlled by administration of a thiazide diuretic. During his last visit (6 months ago) his blood pressure was 130/75 mm Hg and his serum creatinine was 1 mg/100 ml. He has been exercising regularly for the past 2 years, but recently has complained of knee pain and began taking large amounts of a nonsteroidal anti-inflammatory drug. When he arrives at your office, his blood pressure is 155/85 and his serum creatinine is now 2.5 mg/100 ml. Which of the following best explains his increased serum creatinine?
TLS Online TPP Program

#Question id: 12953

#Unit 7. System Physiology – Animal

 Which of the following diuretics inhibits Na+-2Cl−-K+ co-transport in the loop of Henle as its primary action?
TLS Online TPP Program

#Question id: 12952

#Unit 7. System Physiology – Animal

Which of the following changes would tend to increase Ca2+ reabsorption in the renal tubule?
TLS Online TPP Program

#Question id: 12951

#Unit 7. System Physiology – Animal

If the cortical collecting tubule tubular fluid inulin concentration is 40 mg/100 ml and plasma concentration of inulin is 2.0 mg/100 ml, what is the approximate percentage of the filtered water that remains in the tubule at that point?