Barbara McClintock, famous for discovering that genes could move within genomes, had her meticulous work ignored for nearly 4 decades, but eventually won the Nobel Prize. Why was her work so distrusted?

#Question id: 12699

#Unit 7. System Physiology – Animal

#Question id: 1518

#Unit 4. Cell Communication and Cell Signaling

Following statements are regarding to the some cancers harbor characteristic chromosome alterations. Chronic myelogenous leukemia (CML), a common leukemia in humans, was found to be associated with the Philadelphia chromosome.

A. Philadelphia chromosome is generated by a translocation between chromosomes 22 and 9. The two chromosomes exchange their terminal regions, which leads to a characteristic alteration in the size of chromosome 9.

B. At the breakpoint of this translocation, a new fusion protein, the BCR-ABL fusion, is generated.

C. The BCR-ABL fusion protein is a constitutively active kinase that phosphorylates multiple signal-transducing proteins.

D. If this translocation occurs in a hematopoietic cell in the bone marrow, the activity of the chimeric BCR-ABL oncogene dephosphorylate proteins thereby activating many intracellular signal-transducing proteins.

Which of the following statements are incorrect?

#Question id: 7274

#Unit 5. Developmental Biology

The following experiment is designed to study the role of several hormones in the regulation of metamorphosis in frogs.

 If the thyroid gland were removed from the tadpoles in Group 3, metamorphosis would

#Question id: 27378

#Unit 1. Molecules and their Interaction Relevant to Biology

#Question id: 11957

#Unit 7. System Physiology – Animal

Because the foods eaten by animals are often composed largely of macromolecules, animals need to have mechanisms for ________.