TLS Online TPP Program

#Question id: 16966


CCR5 that plays a role in inflammatory response. Unfortunately, this protein is also a key to human immunodeficiency virus (HIV) infection. The virus binds to a loop of the CCR5 protein and then enters the cell. Some people have an allele called Δ32 at the CCR5 locus in which 32 bp are deleted. The missing part of the gene codes for the loop in the protein to which the virus attaches. Which statements is true for CCR5?

#Unit 11. Evolution and Behavior
  1. both homozygous and heterozygous partly resistant to HIV
  2. People who are homozygous for the deletion are partly resistant to HIV, while highly heterozygotes are resistant.
  3. People who are homozygous for the deletion are highly resistant to HIV, while heterozygotes are partly resistant.
  4. both homozygous and heterozygous highly resistant to HIV