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TLS Online TPP Program

#Question id: 2978

The most important regulatory control that restricts cyclins to the appropriate cell cycle stage is ubiquitin mediated, proteasome-dependent protein degradation. Which of the following statement is incorrect regarding to the degradation of protein?

#I Life Science/ Life Sciences Group – I-V

  1. SCF and APC/C are multisubunit ubiquitin-protein ligases that belong to the RING finger family of ubiquitin protein ligases which ensure that the cell cycle engine is driven forward and that cells cannot “go backward” in the cell cycle.

  2. SCF recognizes its substrates only when they are phosphorylated.

  3. The substrate specificity of active, dephosphorylated APC/C is determined in part by its association with one of two related substrate targeting factors called Cdc20 and Cdh1.

  4. The substrates of APC/C contain recognition motifs known as destruction box which is lysine rich.

More Questions
TLS Online TPP Program

#Question id: 18644

#SCPH01 Biochemistry

A laboratory technique used to separate DNA, RNA or protein molecules based on their size and electrical charge.
TLS Online TPP Program

#Question id: 18644

#SCPH06 I Botany

A laboratory technique used to separate DNA, RNA or protein molecules based on their size and electrical charge.
TLS Online TPP Program

#Question id: 18645

#SCPH01 Biochemistry

SDS PAGE separate molecules by size because the presence of SDS (sodium dodecyl sulphate) denatures the protein removing 2˚, 3˚ and 4˚ structures (they assume a linear chain) and the SDS coats the molecules giving them a uniform charge/mass ratio. In an experiment (SDS-PAGE) with a discontinuous buffer system following band pattern is obtained 

   
Choose the correct statement regarding this band pattern
TLS Online TPP Program

#Question id: 18645

#SCPH06 I Botany

SDS PAGE separate molecules by size because the presence of SDS (sodium dodecyl sulphate) denatures the protein removing 2˚, 3˚ and 4˚ structures (they assume a linear chain) and the SDS coats the molecules giving them a uniform charge/mass ratio. In an experiment (SDS-PAGE) with a discontinuous buffer system following band pattern is obtained 

   
Choose the correct statement regarding this band pattern
TLS Online TPP Program

#Question id: 18646

#SCPH01 Biochemistry

Which of the following technique can be used to determine the separation of proteins according to size, and relative molecular mass of proteins.
TLS Online TPP Program

#Question id: 18646

#SCPH06 I Botany

Which of the following technique can be used to determine the separation of proteins according to size, and relative molecular mass of proteins.