TLS Online TPP Program

#Question id: 5071


Defect in hedgehog signaling cause, basal cell nevus syndrome, a rare autosomal dominant condition characterized by both developmental anomalies (fused fingers; rib and facial abnormalities) and multiple malignant tumors. This condition created due to mutation in

#I Life Science/ Life Sciences Group – I-V
  1. smoothened

  2. hedgehog

  3. patched

  4. cubitus interruptus

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TLS Online TPP Program

#Question id: 3680

#SCPH28 | Zoology

If DNA polymerase I were mutated so that all its enzymatic activities were inactive, which part of replication would be most affected?

TLS Online TPP Program

#Question id: 3681

#SCPH01 Biochemistry

 A mutated E. coli cell carries out and completes DNA replication, but the lagging strands are found to contain more errors than normal. These errors are not found evenly distributed throughout the lagging strands, but are found in clusters. Which enzymatic activity is missing from this cell?

TLS Online TPP Program

#Question id: 3681

#SCPH05 I Biotechnology

 A mutated E. coli cell carries out and completes DNA replication, but the lagging strands are found to contain more errors than normal. These errors are not found evenly distributed throughout the lagging strands, but are found in clusters. Which enzymatic activity is missing from this cell?

TLS Online TPP Program

#Question id: 3681

#SCPH06 I Botany

 A mutated E. coli cell carries out and completes DNA replication, but the lagging strands are found to contain more errors than normal. These errors are not found evenly distributed throughout the lagging strands, but are found in clusters. Which enzymatic activity is missing from this cell?

TLS Online TPP Program

#Question id: 3681

#SCPH28 | Zoology

 A mutated E. coli cell carries out and completes DNA replication, but the lagging strands are found to contain more errors than normal. These errors are not found evenly distributed throughout the lagging strands, but are found in clusters. Which enzymatic activity is missing from this cell?

TLS Online TPP Program

#Question id: 3682

#SCPH01 Biochemistry

A mutated strain of E. coli replicates DNA normally at 25°C, but replication stops immediately when the temperature is raised to 37°C. Which protein is likely to be non-functional at the higher temperature?