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TLS Online TPP Program

#Question id: 1652

With reference to the variable Ig domain, which of the following statements is FALSE?

#I Life Science/ Life Sciences Group – I-V

  1. It mediates the secondary consequences of antigen recognition

  2. It has anti-parallel beta-pleated sheet structures

  3. It uses beta-turn loops to bind antigen

  4. It has an extra long beta-turn relative to constant region domains

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TLS Online TPP Program

#Question id: 8290

#I Life Science/ Life Sciences Group – I-V

If, someday, an archaean cell is discovered whose rRNA sequence is more similar to that of humans than the sequence of mouse rRNA is to that of humans, the best explanation for this apparent discrepancy would be ________.
TLS Online TPP Program

#Question id: 672

#I Life Science/ Life Sciences Group – I-V

An ideal α-helix has a pitch of 0.54 nm and a rise of 0.15 nm. What is the length along the helix axis for a segment of an ideal α-helix that contains 30 amino acids?
TLS Online TPP Program

#Question id: 389

#SCPH05 I Biotechnology

A weak acid HA has a pKa of 5.0.  If 1.0 mol of this acid and 0.1 mol of NaOH were dissolved in one liter of water, what would the final pH be?
TLS Online TPP Program

#Question id: 3612

#SCPH28 | Zoology

Multiple alleles control inheritance of
TLS Online TPP Program

#Question id: 16134

#SCPH01 Biochemistry

You obtain 6 BACs (of known order, as shown below) and 7 STSs (of unknown order) that derive from a region of mouse chromosome 16 whose genomic sequence has not yet been finished.   
 
By PCR (using 20-bp primers at either end of each STS), you test each of the 6 BACs for the presence (+) or absence (-) of each of the 7 STSs. You obtain the following results:
 
You determine the DNA sequences of PCR products obtained at STS5 using BACs B, C, D, E, and F as PCR templates. The DNA sequences of PCR products obtained using BACs B and C are identical, but they differ by several nucleotide substitutions from the DNA sequences of PCR products obtained using BACs E and F. Oddly, PCR product obtained using BAC D appears to be a mixture of two sequences – one corresponding to the BAC B/ BAC C sequence and the other corresponding to the BAC E/ BAC F sequence. Briefly account for these findings, and explain how a single PCR assay could amplify two different sequences.