DNA polymerase contains a lysine residue that is important for binding to DNA. Mutations were found that converted this lysine to either glutamate, glycine, valine, or arginine. Which mutations would be predicted to be the most and least harmful to the ability of the enzyme to bind DNA?

	Most	Least
(A)	Valine	Aspartate
(B)	Glycine	Arginine
(C)	Arginine	Glycine
(D)	Glutamate	Arginine

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