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#Question id: 2737


The linking number (Lk) of a closed-circular, double-stranded DNA molecule is changed by:

#SCPH05 I Biotechnology
  1. breaking a strand, unwinding or rewinding the DNA, then rejoining it.

  2. breaking all hydrogen bonds in the DNA.

  3. supercoiling without the breaking of any phosphodiester bonds.

  4. underwinding without the breaking of any phosphodiester bonds.


Answer:- Option(s): 1


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