TLS Online TPP Program

#Question id: 1035


A new drug is developed that inhibits formation of the flagellar filament by impairing production of the protein flagellin. Is this going to be a good drug?

#SCPH06 I Botany
  1. Potentially-it would definitely only impair bacteria, but wouldn't matter for the ones that don't use a flagellum to move around.

  2. Potentially-if it could be shown that it also didn't impair the production of the eukaryotic flagellum.

  3. No-our eukaryotic cells depend on flagella to move around in our body, and this would impair that function.

  4. No-bacterial flagella are produced using microtubules, not the protein flagellin. This drug would be useless in eliminating bacteria.

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TLS Online TPP Program

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TLS Online TPP Program

#Question id: 15817

#SCPH12 I Genetics

You and your lab partner have isolated 20 new mutant yeast strains that are defective in synthesis of threonine, an amino acid. These Thr- mutants do not grow on minimal medium, but they do grow on minimal medium supplemented with threonine. Ten of your Thr- mutants (numbered 1 through 10) were isolated in a strain of mating type a (MAT a). The other 10 Thrmutants (numbered 11 through 20) were isolated in a strain of mating type α (MAT α). You and your lab partner cross each of the MAT a strains to each of the MAT α strains, and you include crosses to the appropriate wild-type strains. Your experimental observations are shown in the table below, where (-) indicates diploids that did not grow on minimal medium and (+) indicates diploids that did grow on minimal medium

Based on these experiments, what is the minimum number of genes required for threonine synthesis?