#Question id: 361
#SCPH01 Biochemistry
Calculate the percentage of histidine that has its imidazole side chain protonated at pH 7.3. The pKa values for histidine are pK1 = 1.8, pK2 (imidazole) = 6.0, and pK3 = 9.2.
#Question id: 2986
#SCPH06 I Botany
During ubiquitin-mediated protein degradation in various events of cell cycle, ubiquitin-protein ligases ubiquitinylate substrate proteins, marking them for degradation by proteasomes. Cyclins are degraded through the action of two different ubiquitin-protein ligases, SCF and the anaphase-promoting complex or cyclosome. Following statements are regarding to SCF and APC/C.
A. SCF controls the G1–S phase transition by degrading G1/S phase cyclins and, CDK inhibitory proteins.
B. APC/C degrades S phase and mitotic cyclins, thereby promoting the exit from mitosis.
C. SCF and APC/C are multi-subunit ubiquitin-protein ligases that belong to the RING finger family of ubiquitin protein ligases.
D. SCF and APC/C belong to the different ubiquitin-protein ligase family, their regulation is same.
E. SCF recognizes its substrates only when they are phosphorylated.
F. SCF and APC/C both recognizes its substrates only when they are phosphorylated.
Which of the following is incorrect?
#Question id: 7011
#SCPH28 | Zoology
The vertebrate brain and spinal cord start their development as a flat plate of neuroepithelial cells that folds up along most of its length to form a tube. The process of forming this neural tube is called neurulation. Which of the following signals play important role in both neurulation and cell fate patterning of neural tube?
#Question id: 1554
#SCPH05 I Biotechnology
Which domain of MHC-1 is interact with CD8 cell surface molecule found on TC cells.
#Question id: 7762
#SCPH01 Biochemistry