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TLS Online TPP Program

#Question id: 12908

Which statement is incorrect about CRISPR?

#SCPH06 I Botany
  1. It  was first identified as an adaptive immunity pathway in prokaryotes providing resistance to bacteriophage and analogous to the RNA interference process found in eukaryotes. 
  2. It does not utilize double-stranded sequence-specific breaks and does not  repair using HDR via homologous recombination.
  3. The system consists of two parts, a short synthetic guide RNA ( gRNA) and a nonspecific double-stranded endonuclease termed Cas9. 
  4. It is also possible to program Cas9 with multiple guide RNAs to allow multiplex site-specific editing for designing large deletions, inversions and translocations.
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TLS Online TPP Program

#Question id: 5219

#SCPH28 | Zoology

What is it that can be duplicated in a genome?
TLS Online TPP Program

#Question id: 5220

#SCPH06 I Botany

In comparing the genomes of humans and those of other higher primates, it is seen that humans have a large metacentric pair we call chromosome #2 among our 46 chromosomes, while the other primates of this group have 48 chromosomes and any pair like the human #2 pair is not present; instead the primate groups each have two pairs of midsize acrocentric chromosomes. What is the most likely explanation?
TLS Online TPP Program

#Question id: 5220

#SCPH28 | Zoology

In comparing the genomes of humans and those of other higher primates, it is seen that humans have a large metacentric pair we call chromosome #2 among our 46 chromosomes, while the other primates of this group have 48 chromosomes and any pair like the human #2 pair is not present; instead the primate groups each have two pairs of midsize acrocentric chromosomes. What is the most likely explanation?
TLS Online TPP Program

#Question id: 5221

#SCPH06 I Botany

Unequal crossing over during Prophase I can result in one sister chromosome with a deletion and another with a duplication. A mutated form of hemoglobin, known as hemoglobin Lepore, is known in the human population. Hemoglobin Lepore has a deleted set of amino acids. If it was caused by unequal crossing over, what would be an expected consequence?
TLS Online TPP Program

#Question id: 5221

#SCPH28 | Zoology

Unequal crossing over during Prophase I can result in one sister chromosome with a deletion and another with a duplication. A mutated form of hemoglobin, known as hemoglobin Lepore, is known in the human population. Hemoglobin Lepore has a deleted set of amino acids. If it was caused by unequal crossing over, what would be an expected consequence?
TLS Online TPP Program

#Question id: 5222

#SCPH06 I Botany

 When does exon shuffling occur?