You are running a human assisted reproduction clinic and providing state-of-the-art genetic diagnostic services. A married couple who already had a child with cystic fibrosis approach you because they wish to have another child, but only if they can be assured that the child will not have cystic fibrosis. You genotype the woman and discover that she is a heterozygote for Del508, the most common mutation causing cystic fibrosis. You suggest that the couple consider first polar body testing, in which several unfertilized oocytes (each with its first polar body) are retrieved from the woman, the first polar bodies are removed, and PCR tests are conducted on DNA from each of the first polar bodies. The couple agrees, and you obtain the following results:

 

Given the couple's desire to have a child without cystic fibrosis, which oocytes would you employ in vitro fertilization?

#Question id: 11067

#I Life Science/ Life Sciences Group – I-V

A preterm infant has a surfactant deficiency. Without surfactant, many of the alveoli collapse at the end of each expiration, which in turn leads to pulmonary failure. Which of the following sets of changes are present in the preterm infant, compared to a normal infant?

#Question id: 11067

#SCPH28 | Zoology

A preterm infant has a surfactant deficiency. Without surfactant, many of the alveoli collapse at the end of each expiration, which in turn leads to pulmonary failure. Which of the following sets of changes are present in the preterm infant, compared to a normal infant?

#Question id: 11068

#SCPH28 | Zoology

A patient has a dead space of 150 ml, functional residual capacity of 3 L, tidal volume of 650 ml, expiratory reserve volume of 1.5 L, total lung capacity of 8 L, and respiratory rate of 15 breaths/min. What is the residual volume?

#Question id: 11069

#I Life Science/ Life Sciences Group – I-V

A 22-year-old woman inhales as much air as possible and exhales as much air as she can producing the spirogram shown in the figure. A residual volume of 1.0 L was determined using the helium dilution technique. What is her functional residual capacity (in liters)?

#Question id: 11069

#SCPH28 | Zoology

A 22-year-old woman inhales as much air as possible and exhales as much air as she can producing the spirogram shown in the figure. A residual volume of 1.0 L was determined using the helium dilution technique. What is her functional residual capacity (in liters)?

#Question id: 11070

#I Life Science/ Life Sciences Group – I-V

A patient has a dead space of 150 ml, functional residual capacity of 3 L, tidal volume of 650 ml, expiratory reserve volume of 1.5 L, a total lung capacity of 8 L, respiratory rate of 15 breaths/min. What is the alveolar ventilation?