#Question id: 5047
#SCPH01 Biochemistry
The process of commitment can be divided into following two stages-
#Question id: 5042
#I Life Science/ Life Sciences Group – I-V
Which one of the following set of Yamanaka factors can be used to regained the pluripotency of somatic cells in mammals?
#Question id: 2986
#SCPH06 I Botany
During ubiquitin-mediated protein degradation in various events of cell cycle, ubiquitin-protein ligases ubiquitinylate substrate proteins, marking them for degradation by proteasomes. Cyclins are degraded through the action of two different ubiquitin-protein ligases, SCF and the anaphase-promoting complex or cyclosome. Following statements are regarding to SCF and APC/C.
A. SCF controls the G1–S phase transition by degrading G1/S phase cyclins and, CDK inhibitory proteins.
B. APC/C degrades S phase and mitotic cyclins, thereby promoting the exit from mitosis.
C. SCF and APC/C are multi-subunit ubiquitin-protein ligases that belong to the RING finger family of ubiquitin protein ligases.
D. SCF and APC/C belong to the different ubiquitin-protein ligase family, their regulation is same.
E. SCF recognizes its substrates only when they are phosphorylated.
F. SCF and APC/C both recognizes its substrates only when they are phosphorylated.
Which of the following is incorrect?
#Question id: 2715
#SCPH05 I Biotechnology
The interaction between the positively charged amino terminus of histone __________ and a negatively charged region of the histone fold domain of histone __________ is particularly important for 30 nm fibre formation.
#Question id: 18658
#SCPH01 Biochemistry