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#Question id: 14148
#I Life Science/ Life Sciences Group – I-V
Dynamic programming determines optimal alignment by matching two sequences for all possible pairs of characters between the two sequences.
Reason(R): Use of the dynamic programming method requires a scoring system to account for matches and mismatches between sequences, and a scheme for Gap penalties.
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#Question id: 15150
#SCPH12 I Genetics
In this problem we will explore some of the many ways that mutations in two different genes can interact to produce different Mendelian ratios. Consider a hypothetical insect species that has red eyes. Imagine mutations in two different unlinked genes that can, in certain combinations, block the formation of red eye pigment yielding mutants with white eyes. In principle, there are two different possible arrangements for two biochemical steps responsible for the formation of red eye pigment. The two genes might act in series such that a mutation in either gene would block the formation of red pigment. Alternatively, the two genes could act in parallel such that mutations in both genes would be required to block the formation of red pigment.
Further complexity arises from the possibility that mutations in either gene that lead to a block in enzymatic activity could be either dominant or recessive. If the crosses is made between a wild type insect with red eyes and a true breeding white eyed strain with mutations in both genes. Such considerations yield the Pathways in series with recessive mutations in both genes, the F1 progeny shows will have red eye, what is the expected phenotypic ratio of red to white eyed insects in the F2.
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#Question id: 4767
#SCPH01 Biochemistry
Neurofibromatosis is a condition in humans which is generally inherited in a dominant fashion. Assuming this disorder is 90% penetrant, what is the chance that a single child born to a father with neurofibromatosis and a mother known not to carry the mutation will have the disorder?
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#Question id: 14831
#I Life Science/ Life Sciences Group – I-V
A spirochete is a member of the phylum Spirochaetota, which contains distinctive diderm gram-negative bacteria, most of which have long, helically coiled cells. Movement of spirochetes occurs by means of structures called
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#Question id: 18217
#SCPH05 I Biotechnology
Which of the following is untrue about homology modeling?