#Question id: 2986
#SCPH06 I Botany
During ubiquitin-mediated protein degradation in various events of cell cycle, ubiquitin-protein ligases ubiquitinylate substrate proteins, marking them for degradation by proteasomes. Cyclins are degraded through the action of two different ubiquitin-protein ligases, SCF and the anaphase-promoting complex or cyclosome. Following statements are regarding to SCF and APC/C.
A. SCF controls the G1–S phase transition by degrading G1/S phase cyclins and, CDK inhibitory proteins.
B. APC/C degrades S phase and mitotic cyclins, thereby promoting the exit from mitosis.
C. SCF and APC/C are multi-subunit ubiquitin-protein ligases that belong to the RING finger family of ubiquitin protein ligases.
D. SCF and APC/C belong to the different ubiquitin-protein ligase family, their regulation is same.
E. SCF recognizes its substrates only when they are phosphorylated.
F. SCF and APC/C both recognizes its substrates only when they are phosphorylated.
Which of the following is incorrect?
#Question id: 18381
#SCPH01 Biochemistry
#Question id: 14142
#SCPH05 I Biotechnology
#Question id: 955
#SCPH05 I Biotechnology
In amino acid catabolism the α-amino groups are initially released as ________.
#Question id: 15912
#SCPH05 I Biotechnology
Match the items in Group 1 with an appropriate description in Group 2
Group 1 Group 2
P. PSI-BLAST 1. ungapped, aligned motif
Q. CLUSTALW 2. Profiles
R. BLOCK 3. Heuristic method
S. FASTA 4. Multiple sequence alignment