TLS Online TPP Program

#Question id: 4143


It is possible to convert the Cys that is a part of Cys-tRNACys to Ala by a catalytic reduction.  If the resulting Ala-tRNACys were added to a mixture of (1) ribosomes, (2) all the other tRNAs and amino acids, (3) all of the cofactors and enzymes needed to make protein in vitro, and (4) mRNA for hemoglobin, where in the newly synthesized hemoglobin would the Ala from Ala-tRNACys be incorporated?

#SCPH01 Biochemistry
  1. Nowhere; this is the equivalent of a nonsense mutation

  2. Wherever Ala normally occurs

  3. Wherever Cys normally occurs

  4. Wherever either Ala or Cys normally occurs

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