Cellular senescence may have evolved to protect organisms against cancer. Instead of dividing out of control, the cells die. Cellular senescence appears to be regulated by several tumor suppressor genes, especially p53.what is the most appropriate reason behind this,

1) Transcription factor p53 is thought to suppress tumorigenesis by causing cell arrest and senescence in response to short telomeres, DNA damage, and viral or external signals to divide

2) This factor can stop the cell cycle, cause cellular senescence in rapidly dividing cells, instruct genes to initiate cellular apoptosis, and activate DNA repair enzymes.

3) Induction of apoptosis or cellular senescence by p53 always beneficial.

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#Question id: 583

#1. Molecules and their Interaction Relevant to Biology

When there are two substrates in a reaction, the reaction is said to be second order if ________.

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#11. Evolution and Behavior

What is it that can be duplicated in a genome?

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#8. Inheritance Biology

Genes for cytoplasmic male sterility in plants are generally located in

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#13. Methods in Biology

In a horse race the odds in favour of four horses H1, H2, H3, H4 are 1 : 3, 1 : 4, 1 : 5; 1 : 6 respectively not more than one wins at a time. Then the chance that one of them wins is

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#5. Developmental Biology

An embryo with meroblastic cleavage, extraembryonic membranes, and a primitive streak must be that of ________.