In Notch/Delta pathway, 

signaling molecule is Delta, an integral membrane protein bound to the surface of the signaling cell.

TLS Online TPP Program

#Id: 5710

#Unit 7. System Physiology – Animal

GHRH- Hypothalamus  stimulates growth hormone secretion by utilizing both cAMP and IP3/Ca2+ as second messengers.

TLS Online TPP Program

#Id: 5711

#Unit 7. System Physiology – Animal

Somatotropes—human growth hormone

promotes growth of the entire body by affecting protein formation, cell multiplication, and cell differentiation.

TLS Online TPP Program

#Id: 5712

#Unit 7. System Physiology – Animal

Principal signaling pathway activated by the growth hormone- JAK–STAT

TLS Online TPP Program

#Id: 5713

#Unit 7. System Physiology – Animal

Somatostatin (somatotropin release–inhibiting hormone) -hypothalamus Inhibit growth hormone secretion.

TLS Online TPP Program

#Id: 5714

#Unit 7. System Physiology – Animal

Somatostatin binds membrane receptor, which is coupled to Galpha i protein.

TLS Online TPP Program

#Id: 5715

#Unit 7. System Physiology – Animal

Before puberty, Growth hormone excess causes gigantism