Cleavage by the γ-secretase complex releases the Notch cytosolic segment, which translocates to the nucleus, interacts with a single DNA-binding transcription factor, CSL.

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#Id: 2634

#Unit 13. Methods in Biology

The probe must span the sequence where the transcript starts or ends. After hybridizing the probe to the transcript, one applies S1 nuclease, which degrades only single-stranded DNA and RNA.

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#Id: 2136

#Unit 8. Inheritance Biology

Recombinant chromosomes have too many copies of some genes and no copies of others, so gametes that receive the recombinant chromosomes cannot produce viable progeny.

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#Id: 7553

#Unit 6. System Physiology – Plant

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#Id: 6760

#Unit 3. Fundamental Processes

RNase E and PNPase, along with a helicase and another accessory enzyme, form a multiprotein complex called the degradosome.

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#Id: 1220

#Unit 7. System Physiology – Animal

When extracellular Ca2+ is decreased decreased Ca2+ binding to the receptor stimulates PTH secretion