Craniorachischisis-combination of anencephaly with a contiguous bony defect of the spine (also without meninges covering the neural tissue –rachischisis)

TLS Online TPP Program

#Id: 7092

#Unit 3. Fundamental Processes

It is complementary to a highly conserved sequence close to the 3’ end of 16S rRNA.

The rRNA sequence is the hexamer:

3’. . . U C C U C C . . . 5’

TLS Online TPP Program

#Id: 7093

#Unit 3. Fundamental Processes

 5’-AUGA-3’ is sequence between overlapping ORFs is known as translational coupling.

TLS Online TPP Program

#Id: 7094

#Unit 3. Fundamental Processes

TLS Online TPP Program

#Id: 7095

#Unit 3. Fundamental Processes

 A series of 3 G-C pairs in the stem that precedes the loop containing the anticodon is unique to tRNAf Met. These base pairs are required to allow the fMet- tRNAf to be inserted directly into the P site.

TLS Online TPP Program

#Id: 7096

#Unit 3. Fundamental Processes

Formylation is not strictly necessary because nonformylated Met-tRNAf can function as an initiator.

TLS Online TPP Program

#Id: 7097

#Unit 3. Fundamental Processes

In bacteria and mitochondria, the formyl residue on the initiator methionine is removed from the protein by a specific deformylase enzyme to generate a normal NH2 terminus.