Negatively charged large molecules are filtered less easily than positively charged molecules of equal molecular size.

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#Unit 6. System Physiology – Plant

The gene that encodes the MYB-related protein is therefore probably a primary response gene, and the LHCB gene itself is probably a secondary response gene.

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#Unit 6. System Physiology – Plant

MYB-related protein, now known as circadian clock associated 1 (CCA1), also plays a role in the circadian regulation of LHCB gene expression.

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#Unit 6. System Physiology – Plant

Second but distinct MYB-related protein, late elongated hypocotyl (LHY), has also been identified as a potential clock gene.

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#Unit 6. System Physiology – Plant

When the CCA1 gene is mutated so that no functional protein is produced, circadian and phytochrome regulation of four genes, including LHCB, is affected.

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#Unit 6. System Physiology – Plant

A protein kinase (CK2)CKB3 can interact with and phosphorylate CCA1, which is a multisubunit protein with serine/threonine kinase activity.

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#Unit 6. System Physiology – Plant

Phytochrome interacting factors (PIFs) act as negative regulators of photomorphogenesis.