Nurturing Life Sciences
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#Unit 7. System Physiology – Animal
SA node has Prepotential or pacemaker potential which is the gradual potential rise from the resting membrane potential to threshold ( -40 mV) & this occur spontaneously.
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Membrane ion channels that play important roles in generation of the action potential:
T (transient) channels
L (long-lasting) channels
Voltage gated potassium ion channel
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Between heartbeats, influx of positively charged sodium ions causes a slow rise in the resting membrane potential in the positive direction.
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When the L-type calcium channels become inactivated at about the same time, greatly increased numbers of potassium channels open.